Short-term treatment of gonorrhoea with intramuscular and oral forms of trimethoprim-sulphamethoxazole.

Short-term treatment of gonorrhoea with intramuscular and oral forms of trimethoprim-sulphamethoxazole.

Fifty-nine male patients and 41 female patients with uncomplicated gonorrhoea were treated with an intramuscular dose of 1600 mg sulphamethoxazole plus 320 mg trimethoprim followed by an oral dose of 2400 mg sulphamethoxazole plus 480 mg trimethoprim 12 hours later. Forty-nine out of 52 male patients and 37 out of 38 female patients who were re-examined were cured. One of the men probably had a...

Sulphamethoxazole-trimethoprim in the treatment of gonorrhoea.

SELECTION OF PATIENTS All patients who attended the Plymouth clinic during that period and from whom smears and cultures yielded gonococci were included in the trial with the following exceptions: (i) Pregnant women (ii) Known prostitutes (iii) Men with gonococcal proctitis (iv) Patients who had defaulted on previous occasions (v) Patients who would be unable to attend for regular follow-up. A ...

Treatment of gonorrhoea with trimethoprim-sulphamethoxazole in Uganda.

Penicillin is still satisfactory as the main treatment for gonorrhoea in Uganda, but there is evidence that its usefulness is declining. In 1961, there was a treatment failure rate of only 4 per cent. with a single dose of 0-3 mega units penicillin aluminium mono-stearate (PAM) (Kibukamusoke, 1965); four times that dose-1V2 mega units-gave a failure' rate of 17-9 per cent. in 1966 (Arya, unpubl...

Trimethoprim-sulphamethoxazole (Septrin) in the treatment of rectal gonorrhoea.

The recent increase in some parts of London of syphilis acquired homosexually (Lancet, 1964; Brit. med. J7., 1967) has indicated that a drug of nontreponemicidal properties is to be preferred in the treatment of gonococcal proctitis in homosexual men. Septrin was considered as a potentially useful remedy in these circumstances. Though taken orally and so subject to error or misuse, it needs be ...

Treatment of gonorrhoea with trimethoprim-sulphamethoxazole and probenecid plus procaine penicillin in Rwanda.